| 冠状动脉粥样硬化患者血清抗HCMV抗体和抗血管内皮细胞抗体的检测及临床意义 |
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| 引用本文： | 姚磊,宋文全,张征,余明芳.冠状动脉粥样硬化患者血清抗HCMV抗体和抗血管内皮细胞抗体的检测及临床意义[J].重庆医学,2000,29(6):500-501. |
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| 作者姓名： | 姚磊 宋文全 张征 余明芳 |
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| 作者单位： | 1. 第三军医大学新桥医院检验科,重庆,400037
2. 第三军医大学检验系 |
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| 摘 要： | 目的：探讨冠状动脉粥样硬化患者的血清抗巨细胞病毒（ＨＣＭＶ）抗体和抗内皮细胞抗体（ＡＥＣＡ）的水平及其与动脉粥样硬化（ＡＳ）的关系。方法：应用细胞酶联免疫反应（Ｃ－ＥＬＩＳＡ）和ＥＬＩＳＡ技术检测４１例冠状动脉粥样硬化患者血清中ＡＥＣＡ和抗ＨＣＭＶ抗体（ＩｇＧ）。结果：４１例冠心病组抗ＨＣＭＶＩｇＧ抗体的阳性率为７３．２％，而对照组阳性率为３１．０％。冠心病组ＡＥＣＡ阳性率为３４．１％。结论：冠心
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| 关 键 词： | 冠状动脉粥样硬化 抗内皮细胞抗体 抗HCMV抗体 |
Detection of Anti-endothelial Cell Antibodies and Anti-Cytomegalovirus Antibodies in the Serum of Patient with coronary atherosclerotic heart disease |
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| Abstract: | Objective:Detection of anti endothelial cell antibodies and anti cytomegalovirus antibodies in the serum of patient with coronary atherosclerotic heart disease and to explore the relationship among CMV, AECA and atherosclerosis.Methods:AEAC were detected in serum samples of 41 patients with AS using cell enzyme linked immunosorbent assay(C ELISA); the CMV(IgG)was analyzed by indirect ELISA.Results:The postive rate of AECA (34.1%)is significantly higher than that in control people;the postive rate of CMV IgG(73.2%) is higher than that of healthy people(31.0%)(P<0.01).Conclusion:CMV infection and AECA are related to atherosclerosis. |
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| Keywords: | Atherosclerosis Anti cytomegalovirus antibody Anti endothelial cell antibody |
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