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Pharmacological characteristics of agonistantagonist analgesics |
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| Authors: | Louis S. Harris |
| Affiliation: | Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, U.S.A. |
| Abstract: | A brief history and pharmacological characteristics of agonist-antagonist analgesics are presented. The importance of this class of compounds on the development of opioid-receptor concepts is described. |
| Keywords: | Author Keywords: Agonist-antagonist analgesics N-allylnorcodeine Nalorphine SKF-10,047 Pentazocine Endogenous opioid peptides Mu, kappa and delta receptors Binding sites |
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