筋膜间隔综合征与脂肪栓塞相关性:临床资料分析

目的 为研究脂肪栓塞发病机制,分析筋膜间隔综合征(compartment syndrome,CS)与脂肪栓塞(fat embolism,FE)之间的相关性.方法 对比长骨骨折合并CS组与无CS的长骨骨折组的(亚)临床FE(＜sub-＞CFE)的发病率、高甘油三酯(HTG)合并尿酮体(++)阳性率,分析CS对(sub-)CFE发病的优势比(OR)及积差相关系数(r).结果 两组sub-CFE发病率分别为16.22%、9.68%.差别有非常显著意义(x2=20.71,P＜0.01);CS对(sub-)CFE、HTG的OR分别为1.94、1.97(CI95＞1);r为0.66(tr=4.96,P＜0.01).结论 上述结果均提示,CS是(sub-)CFE发病的危险因子,相关呈中度.

Correlation between compartment syndrome and fat embolism:an analysis on clinical data

Objective To study the correlation between fat embolism(FE)and compartment syndrome (CS)in the mechanism of the diseases.Methods Controlled studies were undertaken in the 2 groups consisting respectively of 111 cases(OG)with the CS after the fracture of a long bone and 279 cases(CG)with this fracture but without the CS.The prevalcence rate(PB)of fat embolism(FE)was compared.The odd ratio(OR)of CS to FE,to ketenceria concurrent with hypertriglyceridemia was respectively analyzed,and the correlation coefficient(CC)between CS and FE was computed.Reults The PR(16.22%)of sub-CFE in the OG was significantly higher than that(9.68%)in the CG(X2=20.71,P＜0.01).The OR to FE was 1.94(95% CI＞1),the OR to the ketenceria was 1.97(95%CI＞1).The CC was 0.66(tr=4.96,P＜0.01).Conclusion The results suggested that the CS belongs to a risk factor resulting in the FE,their correlation being moderate.