| 受精调控机制的研究进展 |
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| 引用本文： | 黄品秀,韦继红.受精调控机制的研究进展[J].中华妇幼临床医学杂志,2014(1):107-110. |
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| 作者姓名： | 黄品秀 韦继红 |
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| 作者单位： | 广西柳州市妇幼保健院生殖健康助孕中心,广西壮族自治区柳州545001 |
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| 摘 要： | 人类和哺乳动物的受精机制是近年来的研究热点.通过生物化学、转基因和基因敲除等研究得出的受精机制主要分为4个部分：①精子获能;②精子结合至卵子透明带;③精子与透明带结合诱发顶体反应（AR）;④精子与卵子的结合和膜融合.笔者拟就近期研究阐明的精子获能、AR及精、卵融合的新信息、新观点,进行综述如下.
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| 关 键 词： | 受精机制 精子获能 顶体反应 精卵融合 |
Research Progress of Fertilization Regulation Mechanism |
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| Huang Pinxiu,Wei Jihong.Research Progress of Fertilization Regulation Mechanism[J].Chinese JOurnal of Obstetrics & Gynecology and Pediatrics,2014(1):107-110. |
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| Authors: | Huang Pinxiu Wei Jihong |
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| Institution: | . Department of Reproductive Medicine, Maternal and Child Health Care Hospital of Guangwi, Liuzhou 545001, Guangxi Zhuang Autonomous Region, China. |
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| Abstract: | The mechanism of human and mammalian fertilization has been the hot subject in recent years. The fertilization mechanisms according to biochemistry, transgenic and gene knock-out are the following four major aspects, ①sperm capacitation; ②sperm to the ovum zona pellucida;③sperm combined zona pellucida induced acrosome reaetion （AR） ; ④sperm combined ovum and membrane fusion. This paper focuses on the research progress of sperm capacitation, AR, and sperm-ovum fusion. |
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| Keywords: | Fertilization mechanism Sperm capacitation Acrosome reaction Sperm-ovumfusion |
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