| 非小细胞肺癌术后CEA、CYFRA21-1和TNF联合检测的临床意义 |
| |
| 引用本文： | 陶谦,周宣岩,刘淑会.非小细胞肺癌术后CEA、CYFRA21-1和TNF联合检测的临床意义[J].医学检验与临床,2006,17(5):41-42. |
| |
| 作者姓名： | 陶谦 周宣岩 刘淑会 |
| |
| 作者单位： | 山东省聊城市第二人民医院,临清,252601 |
| |
| 摘 要： | 目的探讨定期联合检测血清肿瘤标志物在非小细胞肺癌(NSCLC)预后中的意义。方法采用放射免疫法检测65例NSCLC患者手术前后和35例健康对照组的血清癌胚抗原(CEA)、细胞角蛋白19(CYFRA21-1)和肿瘤坏死因子(TNF)的含量。结果NSCLC组患者血清CEA、CYFRA21-1和TNF的含量均明显高于健康对照组(p<0.01),手术治疗后未复发转移组低于术前(p<0.01),复发转移组明显高于未复发转移组(p<0.01)。结论测定NSCLC患者血清中CEA、CYFRA21-1和TNF水平对患者的治疗和预后均有一定的临床价值。
|
| 关 键 词： | 癌胚抗原 细胞角蛋白19片段 肿瘤坏死因子 非小细胞肺癌 |
Clinical signification of CEA,CYFRA21 - 1 and TNT levels after operation in non-small cell lung cancer |
| |
| Tao Qian,Zhou Xuanyan,Liu Shuhui.Clinical signification of CEA,CYFRA21 - 1 and TNT levels after operation in non-small cell lung cancer[J].Medical Laboratory Science and Clinics,2006,17(5):41-42. |
| |
| Authors: | Tao Qian Zhou Xuanyan Liu Shuhui |
| |
| Abstract: | Objective To study the clinical signification of the serum levels of carbohydrate antigen 125(CEA),cytokeratin 19-fragments(CYFRA21-1) and tumor necrosis factor(TNF) in patients with Non-Small Cell Lung Cancer(NSCLC).Methods Serum CEA,CYFRA21-1 and TNF levels were determined by with RIA in 65 NSCLC both before and after operation as well as in 35 controls.Results Operation,serum CEA,CYFRA21-1 and TNF levels in the NSCLC were significantly higher than those in the controls(p<0.01).The levels of CEA,CYFRA21-1 and TNF lower than that before surgery(p<0.01).Recrudesece group are higher than non-recrudesce group(p<0.01).Conclusion The serum levels of CEA,CYFRA21-1 and TNF are closely related to the tumor burden and may reflect the presence of recurrence. |
| |
| Keywords: | CEA CYFRA21-1 TNF Non-small cell lung cancer |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
