Cytotoxic lipid esters from Peucedanum ledebourielloides |
| |
| Authors: | Xing Zheng Jiang Du Yunlong Xu Duanfang Liao George R Pettit |
| |
| Institution: | (1) Institute of Pharmacy and Pharmacology, Nanhua University, Hengyang, 421001, People’s Republic of China;(2) Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA;(3) Department of Chemistry, Colorado State University, Fort Collins, CO 80526, USA;(4) State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, People’s Republic of China |
| |
| Abstract: | Two cancer cell growth inhibitory esters, 1,2-dipalmitoyl-3-glucosyl glycerol (1) and 1,6-dihydroxy-hexane-bis-palmitoyl ester (2), together with arachidic acid-2-hydroxy-glycerol ester, daucosterol, and oleanolic acid, were isolated from the roots of
Peucedanum ledebourielloides (Apiaceae family). The structures were determined by spectroscopic analyses. The esters 1 and 2 displayed significant activity against the SGC-7901, HT-29, and HL-60 cancer cell lines. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
