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大肠癌S-100~+树突状细胞和预后的关系
引用本文:刘思纯,袁世珍. 大肠癌S-100~+树突状细胞和预后的关系[J]. 实用肿瘤杂志, 1996, 0(5)
作者姓名:刘思纯  袁世珍
作者单位:中山医科大学孙逸仙纪念医院消化疾病研究室,中山医科大学附属第一医院消化内科
摘    要:
用S-100蛋白质抗体对71例不同预后的大肠癌患者原位癌组织进行ABC免疫组化染色。结果表明术后生存期≥5年者癌组织S-100+树突状细胞DC)数量明显高于术后生存期<5年者(P<0.001)。在具有同一种病理因素的患者中,生存期不同者其癌组织DC数量差异有显著性。揭示癌组织DC数量可作为估计患者预后的指标之一。

关 键 词:大肠癌,S-100蛋白,树突状细胞,预后

The relationship between S-100 protein-positive dendritic cells and prognosis of colorectal carcinomas
Liu Sichun et al. The relationship between S-100 protein-positive dendritic cells and prognosis of colorectal carcinomas[J]. Journal of Practical Oncology, 1996, 0(5)
Authors:Liu Sichun et al
Abstract:
Dendritic cells (DC) in paraffin-embeded tissue were measured with ABC immunohistochemial method using S-100 protein antibody from 71 cases of colorectal carcinomas. Quantitative analysis showed that the patients who survived longer than 5 years had significantly higher DC number in primary tumor than those less than 5 years (P<0.001). Irrespective of othet morphologic fectures, there was a statistically significant difference between two groups (P<0.01). The results suggests that the amount of DC in situ might be used as an indicator in assessing prognosis of colorectal carcinoma.
Keywords:colorectal carcinoma  S-100 protein  dendritic cells  prognosis
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