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| 低氧习服过程对模拟高原急性低氧大鼠肺组织结构的影响 | |
| 引用本文： | 李福祥,徐朝霞,夏前明,全燕,李鸿雁,张彦. 低氧习服过程对模拟高原急性低氧大鼠肺组织结构的影响[J]. 西南国防医药, 2008, 18(2): 160-163 |
| 作者姓名： | 李福祥 徐朝霞 夏前明 全燕 李鸿雁 张彦 |
| 作者单位： | 1. 成都军区总医院呼吸内科,四川,成都,610083 2. 成都军区总医院急诊科,四川,成都,610083 |
| 基金项目： | 全军医药卫生科研基金资助项目(01MB038) |
| 摘 要： | 目的：观察低氧习服对模拟高原低氧大鼠肺组织的影响。方法：32只Vistar大鼠随机分成4组：常氧对照组（N组，n=8）、急性低氧组（H组，n=8）、3000m低氧习服＋急性低氧组（G组，n=8）、5000m低氧习服＋急性低氧组（（=5组，n=8）。习服完成后，置于模拟海拔6000m急性低氧24h，观察动物在不同低氧习服水平对模拟高原急性低氧大鼠肺组织结构改变。结果：急性低氧组大鼠肺组织显微和超微结构出现少量的肺泡性肺水肿，明显的间质性肺水肿；而经过低氧习服后，间质性肺水肿明显减轻，基本无肺沿幽市水肿出现。结论：低氧习服可以明显减轻急性低氧大鼬市水肿特别是间质肺水肿的程度。 |
| 关 键 词： | 低氧习服 肺水肿 高原 |
| 文章编号： | 1004-0188(2008)02-0160-03 |
| 修稿时间： | 2007-11-28 |
Effects of hypoxic preconditioning on pulmonary structure of rats exposed rapidly to simulated high altitude hypoxia |
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| LI Fu-xiang,XU Zhao-xia,XIA Qian-ming,QUAN Yan,LI Hong-yan,ZHANG Yan. Effects of hypoxic preconditioning on pulmonary structure of rats exposed rapidly to simulated high altitude hypoxia[J]. Medical Journal of National Defending forces in Southwest China, 2008, 18(2): 160-163 | |
| Authors: | LI Fu-xiang XU Zhao-xia XIA Qian-ming QUAN Yan LI Hong-yan ZHANG Yan |
| Affiliation: | LI Fu-xiang1,XU Zhao-xia2,XIA Qian-ming1,QUAN Yan1,LI Hong-yan1,ZHANG Yan1 1.Department of Respiratory Medicine,General Hospital of Chengdu Military Comm,,Chengdu,610083,China,2.Department of Emergency,China. |
| Abstract: | Objective:To investigate the effects of hypoxic preconditioning on pulmonary structure of rats exposed rapidly to simulated high altitude hypoxia.Methods:Thirty-two Wistar rats were randomly divided into four groups: normal control group (N group, n=8), acute hypoxic group (H group, n=8), 3 000 m hypoxic preconditioning + acute hypoxic group (C3 group, n=8), 5 000 m hypoxic preconditioning + acute hypoxic group (C5 group, n=8). After treated with hypoxic preconditioning according to different hypoxic condit... |
| Keywords: | hypoxic preconditioning pulmonary edema high altitude. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |