血管内超声对冠状动脉粥样斑块和介入性治疗的评价研究

本研究通过对８７例患者包括９７支病变血管在ＰＴＣＡ和ＤＣＡ前后的形态特征的观察，结果显示ＩＶＵＳ对斑块钙化和冠状动脉夹层的检出率高于ＣＡＧ检查，是一项可以对粥样斑块形态特征做出准确评价的敏感的影像技术，并能对各种介入性冠状动脉治疗后血管壁及斑块的形态改变做出定性和定量的评价。ＰＴＣＡ后导致被扩张的血管内腔面积增大是由血管壁扩张和夹层共同作用的结果，而在ＤＣＡ之后管腔面积增加的主要机理是斑块的减少。

Intravascular Ultrasound of Atherosclerotic Vessels:Changes Observed during Coronary Intervention

We evaluated the morphology of the plaque before and after PTCA and IX:A using a high frequency intravascular ultrasound imaging catheter.IVUS was performed at 97 lesions in 87 patients before and after corornary intervention(PTCA in 69 lesions,DCC A in 28 lesions),IVUS appeared to be more sensitive than angiography for demonstrating the presence of coronary dissection and plaque calcification.The improvement in lumen area after PTCA is a result of both vessel stretch and dissection demonstrated by a larger cross sectional vessel area at the treated site.and dissection. Both vessel stretch and dissection are uncommon after DCA,a find ing consistent with plaque removal as the major mechanism for improved lumen area after this procedure.