Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UK |
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| Authors: | Linda Penn Martin White John Oldroyd Mark Walker K George MM Alberti John C Mathers |
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| Affiliation: | (1) Public Health Research Programme, Institute of Health and Society, Newcastle University, NE24HH Newcastle upon Tyne, UK;(2) Human Nutrition Research Centre, Institute for Ageing and Health, Newcastle University, NE24HH Newcastle upon Tyne, UK;(3) Diabetes Research Group, Newcastle University, NE24HH Newcastle upon Tyne, UK;(4) Medicine, Nursing and Health Sciences, Monash University, 3800, Victoria, Australia;(5) Institute of Cellular Medicine, Newcastle University, NE24HH Newcastle upon Tyne, UK;(6) Department of Endocrinology and Metabolism, St Mary's Hospital and Imperial College, University of London, W2 1NY London, UK |
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| Abstract: | ![]()
Background Diabetes prevalence is increasing. The Finnish Diabetes Prevention Study (DPS) showed a 58% reduction in Type 2 Diabetes (T2D) incidence in adults with impaired glucose tolerance (IGT). The European Diabetes Prevention Study (EDIPS) extends the DPS to different European populations, using the same study design. In the Newcastle arm of this study (EDIPS-Newcastle), we tested the hypothesis that T2D can be prevented by lifestyle intervention and explored secondary outcomes in relation to diabetes incidence. |
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