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血清S100蛋白与星形细胞瘤放射性脑损伤的关系
摘    要:


关 键 词:S100蛋白 星型细胞瘤 放射性脑损伤

Serum S100 protein and radiation-induced brain injury in astrocytoma patients]
Wei-shu Song,Li-bing Guo,Zhi-yong Hong,Jun-Jie Li,Jun Wu. Serum S100 protein and radiation-induced brain injury in astrocytoma patients][J]. Journal of First Military Medical University, 2005, 25(6): 723-725
Authors:Wei-shu Song  Li-bing Guo  Zhi-yong Hong  Jun-Jie Li  Jun Wu
Affiliation:Department of Oncology, Second People's Hospital of Guangdong Province, Guangzhou 510317, China.
Abstract:
OBJECTIVE: To study the value of serum S100 protein in the diagnosis of radiation-induced brain injury in astrocytoma patients. METHODS: Serum S100 protein levels were detected by enzyme-linked immunosorbent assay in 86 astrocytoma patients in the course of radiotherapy. RESULTS: The positivity rates of serum S100 protein before, in the middle of and after radiotherapy were 0, 9.3% (8/86) and 19.8% (17/86), respectively, showing significant differences (P<0.05) between these time points for measurement. CONCLUSION: High levels of serum S100 protein are associated with radiation-induced brain injury in astrocytoma patients and may serve as the marker for early diagnosis of the injury.
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