上海市浦东新区2005-2007年手足口病疫情监测分析

[目的]探讨浦东新区手足口病的流行病学和病原学特征。[方法]使用国家疾病监测信息管理系统开展手足口病监测,并对部分病例进行病原体检测。[结果]手足口病是浦东新区儿童中发病率较高的一种传染病,2~5岁组儿童发病率达1000/10万以上,男性多于女性,5—7月为发病高峰季节,在托幼机构易引起爆发。采集疱疹液43份,经RT-PCR检验,17份为肠道病毒71型(EV 71)阳性,阳性率为39.53%,4份为柯萨奇病毒A16型(CoxA16)阳性,阳性率为9.3%。[结论]手足口病的发生有明显年龄、性别、季节差异,EV71是近年来引起儿童手足口病的主要病原体,开展手足口病流行病学和病原学研究,将有助于提出更好的预防和控制措施。

Surveillance and analysis of hand-foot-mouth disease in Pudong New Area 2005-2007

[ Objective] To find out the epidemiological characteristics and the important pathogens of hand - foot - mouth disease （ HFMD ）. [ Methods] Surveillance and report was done according to national disease supervision information management system of hand - foot - mouth disease. Some patients were diagnosed through RT - PCR. [ Results] It was found that hand -foot -mouth disease was one of the infectious diseases with high incidence in Children. The incidence of children aged 2 to 5 exceeded 10/1000 and outbreaks used to occur at nurseries and kindergartens, with obvious peak season in summer. The incidence differed between male and female. The positive rate of EV71 was 39.53 % （ 17/43 ） , The positive rate of CoxA16 was 9.30 % （4/43）. [ Conclusion] Incidence differs between sexes, seasons and ages. The important pathogen of HFMD is EV71. To study the epidemiological characteristics and etiology of hand - foot - mouth disease helps to suggest better control and prevention it in future.