采用同伴推动抽样法在重庆市男男性行为人群中开展HIV流行病学调查

目的 了解重庆市男男性行为(MSM)人群HIV的感染状况和相关危险因素,并探索同伴推动抽样方法(RDS)的可行性.方法 在前期定性调查的基础上,采用RDS对MSM人群进行抽样,用标准化问卷收集行为学信息并采集血液样本进行HIV和梅毒的血清学检测,采用RDSAT软件对数据进行权重处理并用SPSS软件进行单因素分析,NETDRAW软件作网络招募图.结果 经RDSAT软件调整后,在617名招募者中,HIV和梅毒的感染率分别为16.8%和10.9%.其中20～29岁组占73.0%,72.9%是本地人,83.4%未婚,学生的构成比最高占24.6%.最近半年83.4%的调查者有肛交行为,54.0%的人有无保护性肛交性行为.梅毒阳性与HIV感染状况密切相关.结论 重庆市MSM人群的HIV感染率处于较高水平;在重庆市MSM人群较活跃的地区RDS方法是简便可行的,相对于滚雪球法可招募到更多不常去"同志场所"的目标人群.

A respondent-driven sampling survey on HIV and risk factors among men who have sex with men in Chongqing

Objective To examine HIV prevalence and related risk factors among men who have sex with men(MSM) in Chongqing, and to explore the feasibility of using respondent-driven sampling (RDS) in the survey. Methods Based on results from formative research, a RDS survey was designed and conducted to collect demographic, behavioral and serologic data. RDSAT was used to calculate point estimation and confidence intervals. SPSS was used for bi-variate analysis using RDSAT exported weighed data. NETDRAW was used to draw network diagram. Results Among 617 subjects recruited, the adjusted HIV and syphilis prevalence rates were 16.8% and 10.9%, respectively. 73.0% of the subjects were 20 to 29 years old and 72.9% were officially registered residents of Chongqing. 83.4% were single, with the proportion of students the highest, accounting for 24.6%. During the last six months, 83.4% of them reported ever having anal sex, and 54.0% reported having unprotected anal sex. Conclusion This survey confirmed that Chongqing had a higher reported HIV prevalence among MSM than from other Chinese cities. Comprehensive intervention services were required to address this alarmingly high prevalence, with focus on intervention through internet and those having syphilis infection. RDS seemed one of the effective ways of recruiting hidden MSM populations in Chongqing which had a large population of active MSM who did not frequently visit MSM venues as compared with snowball method.