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喉癌花生凝集素受体的研究
引用本文:吴玉瑛,李福全,董明敏,朱丽雅. 喉癌花生凝集素受体的研究[J]. 郑州大学学报(医学版), 1995, 0(3)
作者姓名:吴玉瑛  李福全  董明敏  朱丽雅
作者单位:河南医科大学第一附属医院耳鼻咽喉科
摘    要:
应用ABC免疫组化技术观察了17例喉癌、癌旁及正常喉粘膜上皮内花生凝集素(PNA)受体的分布。结果表明癌细胞PNA呈强阳性染色,毗邻正常喉粘膜上皮细胞未见阳性表达;在不同的喉癌组织学分级之间,PNA的表达呈不同程度,其差异具有显著性(P<0.005)。提示PNA受体可能是喉癌的一种重要标志,其分布与喉癌的分化、增殖有关,并为喉癌早期诊断和鉴别诊断提供了一种辅助手段。

关 键 词:凝集素;受体;喉;鳞状细胞癌

Study on the peanut lectin receptors in laryngeal carcinoma
Wu Yuying,Li Fuquan,Dong Mingmin,Zhu Liya. Study on the peanut lectin receptors in laryngeal carcinoma[J]. Journal of Zhengzhou University: Med Sci, 1995, 0(3)
Authors:Wu Yuying  Li Fuquan  Dong Mingmin  Zhu Liya
Abstract:
The distribution of peanut lectin(PNA)receptors in 17 cases of laryngeal carcinoinas,epithelial cells adjacent to cancer and normal laryngeal epithelial cells were studied by an ABC immunohistochemical survey.The results showed that PNA appeared to be strongly positive in cancer cells,and there was no positive expression in nearby normal epithelial cells. The expression of PNA was significantly different between the different histopathological grades of carcinomas(P<0. 005). The present study suggests that PNA receptor may be an important marker of laryngeal carcinoma. And its distribution may be related to cancer. The demonstration of PNA receptor could be used as a necessory way for the early and differential diagnoses of larngeal carcinoma.
Keywords:lectin  receptor  larynx  squamous cell carcinoma  
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