| 大肠癌干细胞研究现状及临床应用前景 |
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| 引用本文： | 吴琼,王红,李瑜元. 大肠癌干细胞研究现状及临床应用前景[J]. 国外医学:内科学分册, 2007, 34(12): 705-707 |
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| 作者姓名： | 吴琼 王红 李瑜元 |
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| 作者单位： | 广州医学院附属市一医院消化内科,广东,广州,510180;广州医学院附属市一医院消化内科,广东,广州,510180;广州医学院附属市一医院消化内科,广东,广州,510180 |
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| 基金项目： | 广州市医药卫生科技重点项目(2006-ZDi-16) |
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| 摘 要： | 大肠癌临床常见。有研究表明,大肠癌起源于大肠隐窝干细胞,其基因突变和异常增殖导致大肠癌发生。通过靶向干扰大肠癌干细胞及其异常的调节信号传导通路,可为大肠癌的治疗开辟新的途径。
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| 关 键 词： | 大肠癌 干细胞 治疗 |
| 文章编号： | 1004-2369（2007）12-0705-03 |
| 收稿时间： | 2007-04-26 |
| 修稿时间： | 2007-08-16 |
Advance in experimental and clinical development of stem cells from colorectal cancer |
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| WU Qiong,WANG Hong,LI Yu-yuan. Advance in experimental and clinical development of stem cells from colorectal cancer[J]. Foreign Medical Sciences(Section of Internal Medicine), 2007, 34(12): 705-707 |
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| Authors: | WU Qiong WANG Hong LI Yu-yuan |
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| Abstract: | Colorectal cancer is one of the most common malignant tumors in humans.It is demonstrated that the cancer cells originated from intestinal crypt stem cells,which are responsible for gene mutation,abnormal tissue proliferation and then cancer formation.Investigation into the nature of cancer stem cells and their signal transduction pathway may help to develop new therapeutic strategies for colorectal cancer treatment. |
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| Keywords: | Colorectal cancer Stem cells Treatment |
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