个性化微创尿激酶灌注负压引流治疗外伤性硬膜外血肿

目的观察个性化微创尿激酶灌注负压引流治疗外伤性硬膜外血肿的临床效果。方法选取我院自2006年3月至2010年5月收治的120例外伤性硬膜外血肿患者随机分为观察组(微创尿激酶灌注负压引流治疗组)64例和对照组(传统骨瓣开颅血肿清除术组)56例,比较两组患者的临床效果。结果①两组患者手术均获成功,出院时GCS评分15分,均无死亡病例发生。观察组患者术后均3-5d顺利拔管,无1例行二次开颅手术。对照组患者2例患者因血肿清除不彻底,于术后2-8d施行微创清除术治疗后痊愈。②两组患者手术时间、术中出血量、术后并发症、住院时间方面比较差异显著(P<0.01),具有统计学意义。结论个性化微创尿激酶灌注负压引流治疗外伤性硬膜外血肿效果理想,且具有创伤小、术后恢复快、并发症少等优点,值得推广应用。

Personalized Minimally Invasive Urokinase Infusion Suction Drainage Treatment of Traumatic Epidural Hematoma

To observe the personalized microtranma urokinase perfusion drainage for treatment of traumatic extradural hematoma clinical effect. Methods In our hospital from 2006 March to 2010 May treated 120 cases of traumatic epidural hematoma patients were randomly divided into the observation group （microtrauma urokinase perfusion drainage with negative pressure treatment group） and control group of 64 cases （traditional bone flap craniotomy group ） in 56 patients, comparing the two groups of patients with clinical effect. Results ~In two groups of patients with operation were successful, the discharge GCS score of 15 points, no deaths occurred. In the observation group 3-5 days after operation were extubated smoothly, without a routine two craaiotomy operation. Patients in the control group of 2 patients with hematoma removal is not thorough, after the operation of 2 - 8D performing minimally invasive surgery recovered after treatment. In two groups of patients with operation time, intraoperative blood loss, postoperative complications, length of hospital stay compared with significant difference （P〈O.OI）, with statistical significance. Conclusion Personalized micro-trauma urokinase perfusion drainage for treatment of traumatic extradural hematoma effect is ideal, and with less trauma, faster postoperative recovery, less complication, is worth promoting the application.