| 视网膜神经节细胞的保护和修复 |
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| 引用本文： | 姚静,徐格致. 视网膜神经节细胞的保护和修复[J]. 眼科研究, 2004, 22(6): 662-665 |
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| 作者姓名： | 姚静 徐格致 |
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| 作者单位： | 200031,上海,复旦大学附属眼耳鼻喉科医院眼科 |
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| 摘 要： | 视网膜神经节细胞(RGCs)的进行性死亡是许多视网膜和视神经疾病发展到最后的必经之路。长期以来一直认为，由于抑制性环境的存在，视神经损伤后不能再生和修复，现在研究证实，在特定的条件下，尽管RGCs的胞体或轴突受损，仍能免于死亡，而且变性的轴突能再生，并能与靶组织建立突触联系。对RGCs的保护和修复的研究进展作一综述。
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| 关 键 词： | 视网膜神经节细胞 凋亡 再生 干细胞 |
Protection and repair of retinal ganglion cells |
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| Yao Jing. Protection and repair of retinal ganglion cells[J]. Chinese Ophthalmic Research, 2004, 22(6): 662-665 |
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| Authors: | Yao Jing |
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| Affiliation: | Yao Jing. Department of Ophthalmology,Affiliated Eye Ear Nose Throat Hospital of Fudan University,Shanghai 200031,China |
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| Abstract: | Retinal ganglion cells' progressive loss is a common pathway for many retinal and optic nerve diseases. It has been known for a long time that optic nerve can not regenerate and repair after injury because of the inhibitory environment. Now, it has been demonstrated that under certain condition retinal ganglion cells can survive,regenerate and contact with their targets, although their body or axon has been injured. The researches of retinal ganglion cells' protection and repair are discussed in this article. |
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| Keywords: | retinal ganglion cell apoptosis regeneration stem cell |
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