肝衰竭实验室检测的临床价值及新指标评价

肝衰竭的病因及临床类型复杂、并发症较多、病程进展较快、临床干预措施存在多样性，因此很难用单一某项实验室指标来准确地评价肝功能受损的程度及精确地预测肝衰竭的预后。近年来，一些反映肝衰竭预后评价的新的生物标志物、生化指标不断涌现，如何将这些新的指标结合经典的多种肝脏功能实验及生化检测指标纳入判断肝衰竭预测预后指标中，从而不断完善现有的反映肝衰竭病情严重程度和预后判断相关的评分系统和生物指标仍须要进行大量研究工作及临床验证。

Clinical implications of laboratory tests in liver failure and evaluation of new laboratory indices for liver failure

As liver failure is associated with a complex etiology, complicated clinical types, a wide range of complications, rapid progression, and varied clinical interventions, it is difficult to use a single laboratory index to accurately evaluate the degree of liver function damage and accurately predict the prognosis of liver failure. With the recent emergence of a variety of novel biomarkers and biochemical indices for assessment of the prognosis of liver failure, extensive research work is needed to study how to combine these new indices with classic liver function tests and biochemical indices for prediction of the prognosis of liver failure. This effort will help to refine the existing scoring system and biomarkers for severity assessment and prognosis prediction of liver failure.