女性生殖道支原体感染与妊娠的关系及药物敏感性

目的:探讨女性生殖道支原体感染与妊娠的关系及药物敏感性。方法:用珠海银科支原体药敏试剂盒对患者组及对照组共418份宫颈分泌物作培养鉴定及药敏试验。结果:患者组支原体的阳性率(67.6%)与对照组(7.0%)比较,患者组明显高于对照组(P<0.01);患者组中的不孕组(67.1%)、习惯性流产组(67.9%)、死胎组(66.7%)之间支原体阳性率无显著差异(P>0.01),但与对照组(7.0%)比较均有显著差异(P值均<0.01)。对10种抗生素的敏感性由高到低依次为:美满霉素、强力霉素、壮观霉素、克拉霉素、司帕沙星、氧氟沙星、环丙沙星、交沙霉素、阿奇霉素、罗红霉素。结论:女性生殖道支原体感染不仅可引起不孕,而且还可导致不良的妊娠结局,如习惯性流产及死胎等;支原体药敏以美满霉素、强力霉素敏感性高。

Explore the relationship between the reproductive tract infection of mycoplasma and pregnancy in women and drug sensitivity test

Objective:To explore the relationship between the reproctove tract infection of mycoplasma and pregnancy in women and drug sensitivity.Methods:418 cases of cervical secretions were cultured and identified to perform drug sensitivity tests using drug-sensitivity kit of mycoplasma produced by Yinke,Zhuiai.Results:418 cases of cervical secretions in women were detected,67.6% cases were positive from the patients,compared to 7.0% in control (P<0.01);the mycoplasma postive rate in sterility was 67.1%,that in RSA 67.9%,that in dead embryo 66.7%,that in others 7.0%,which showed significant differences(P<0.01).The ten antibiotics sensitivity from high to low was as follow: minomycin,doxycycline,spectinomycin,clarithromycin,sparfloxacin, ofloxacin,ciprofloxacin,josamycin,azithromvcin,roxithromycin.Conclusion:Mycoplasma infection of reproductive tract can cause NGU,sterility,RSA and dead embryo.Minomycin and doxycycline are of choice.