| HPLC测定青萘伯喹片中萘酚喹的含量 |
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| 引用本文： | 詹利之,杨家庆,林燕芳,杨兆丽,詹爱琼,张美义,李国桥.HPLC测定青萘伯喹片中萘酚喹的含量[J].中国实验方剂学杂志,2012,18(20):103-105. |
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| 作者姓名： | 詹利之 杨家庆 林燕芳 杨兆丽 詹爱琼 张美义 李国桥 |
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| 作者单位： | 1. 广州中医药大学青蒿研究中心,广州,510405
2. 广州中西医结合医院药剂科中心药房,广州,510800 |
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| 摘 要： | 目的:建立高效液相色谱法测定青萘伯喹片中萘酚喹含量。方法:采用Diamonsil ODS C18柱(4.6 mm×250mm,5μm);乙腈-0.25%二乙胺溶液(磷酸调节pH至2.5)(23∶77)为流动相,流速0.8 mL.min-1,检测波长为342 nm,柱温25℃。结果:萘酚喹在0.16～0.8 mg.L-1与峰面积呈良好的线性关系(r=0.999 976,n=5),平均加样回收率为99.56%,RSD 0.32%(n=9)。结论:该法操作简便、准确,适用于复方制剂青萘伯喹片中萘酚喹的含量测定。
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| 关 键 词： | 含量测定 高效液相色谱法 青萘伯喹片 萘酚喹 |
| 收稿时间： | 2012/3/26 0:00:00 |
Determination of Naphthoquine in Artemisinine Naphthoquine Primaquine Tablets by HPLC |
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| ZHAN Li-zhi,YANG Jia-qing,LIN Yan-fang,YANG Zhao-li,ZHAN Ai-qiong,ZHANG Mei-yi and LI Guo-qiao.Determination of Naphthoquine in Artemisinine Naphthoquine Primaquine Tablets by HPLC[J].China Journal of Experimental Traditional Medical Formulae,2012,18(20):103-105. |
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| Authors: | ZHAN Li-zhi YANG Jia-qing LIN Yan-fang YANG Zhao-li ZHAN Ai-qiong ZHANG Mei-yi and LI Guo-qiao |
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| Institution: | Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China;Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China;Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China;Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China;Central pharmacy of Pharmacy Department,Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou 510800,China;Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China;Research Center for Artemisia Annual L., Guangzhou University of Chinese Medicine, Guangzhou 510405,China |
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| Abstract: | |
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| Keywords: | quantitative determination HPLC Artemisinine Naphthoquine Primaquine Tablets naphthoquine |
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