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Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data
Authors:François-Clément Bidard  Dieter J Peeters  Tanja Fehm  Franco Nolé  Rafael Gisbert-Criado  Dimitrios Mavroudis  Salvatore Grisanti  Daniele Generali  Jose A Garcia-Saenz  Justin Stebbing  Carlos Caldas  Paola Gazzaniga  Luis Manso  Rita Zamarchi  Angela Fernandez de Lascoiti  Leticia De Mattos-Arruda  Michail Ignatiadis  Ronald Lebofsky  Stefan Michiels
Affiliation:1. Department of Medical Oncology and SIRIC, Institut Curie, Paris, France;2. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA;3. Translational Cancer Research Unit, GZA Hospitals Sint-Augustinus, Antwerp, Belgium;4. University of Antwerp, Antwerp, Belgium;5. Department of Gynecology and Obstetrics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany;6. Division of Medical Senology, European Institute of Oncology, Milan, Italy;7. Clinical Laboratory, Hospital Arnau de Vilanova, Valencia, Spain;8. University Hospital of Heraklion, Heraklion, Greece;9. Department of Transfusion Medicine, Laboratory for Stem Cells Manipulation and Cryopreservation, AO Spedali Civili di Brescia, Brescia, Italy;10. AZ Istituti Ospitalieri di Cremona, Cremona, Italy;11. Department of Oncology, Hospital Clinico San Carlos, Department of Medicine, University Complutense of Madrid, Spain;12. Imperial College and Imperial College Healthcare NHS Trust, London, UK;13. Cancer Research UK Cambridge Institute and Department of Oncology, Li Ka Shing Centre, University of Cambridge, Cambridge, UK;14. Cambridge Experimental Cancer Medicine Centre, Addenbrooke''s Hospital, Cambridge University Hospital NHS Foundation Trust, and NIHR Cambridge Biomedical Research Centre, Cambridge, UK;15. Cambridge Breast Unit, Addenbrooke''s Hospital, Cambridge University Hospital NHS Foundation Trust, and NIHR Cambridge Biomedical Research Centre, Cambridge, UK;p. Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy;q. Hospital 12 de Octubre, Madrid, Spain;r. IOV-IRCCS, Padova, Italy;s. Hospital de Navarra, Pamplona, Spain;t. Val d''Hebron Institute of Oncology, Val d''Hebron University Hospital, and Universitat Autònoma de Barcelona, Barcelona, Spain;u. Department of Medical Oncology and Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium;v. Department of Oncology, KU-Leuven, Leuven, Belgium;w. Division of Laboratory Medicine, European Institute of Oncology, Milan, Italy;x. Frauenklinik, University of Ulm, Ulm, Germany;y. Clinical oncology, Hospital Arnau de Vilanova, Valencia, Spain;z. Saarland University, Homburg, Germany;11. International Drug Development Institute, Louvain-La-Neuve, Belgium;12. Department of Tumor Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;13. Université Paris Descartes, Paris, France;14. Service de Biostatistique et d''Epidémiologie, Gustave Roussy, Université Paris-Sud, Villejuif, France
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