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S100A Proteins as Molecular Targets in the Ocular Surface Inflammatory Diseases
Authors:Louis Tong  Wanwen Lan  Rayne R. Lim  Shyam S. Chaurasia
Affiliation:1. Ocular Surface Research Group, Singapore Eye Research Institute, Singapore;2. Department of Cornea and External Eye Disease, Singapore National Eye Center, Singapore;3. Office of Clinical Science, Duke-NUS Graduate Medical School, Singapore;4. Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;5. SRP Neuroscience and Behavioral Disorders, Duke-NUS Graduate Medical School, Singapore;1. Department of Ophthalmology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan;2. Department of Stem Cell Biology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan;3. Department of Dermatology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan;4. Department of Ophthalmology and Regenerative Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan;5. Department of Infectious Diseases, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan;6. Miyata Eye Hospital, Miyakonojo, Japan;1. Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan;2. Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan;3. Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan;4. Department of Public Health, China Medical University, Taichung, Taiwan;5. Department of Ophthalmology, Taipei City Hospital Zhongxing Branch, Taipei, Taiwan;6. Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan;1. Department of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA;2. Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA;1. Department of Ophthalmology, University of Erlangen-Nürnberg, Erlangen, Germany;2. Department of Ophthalmology, University of Cologne, Cologne, Germany;1. Department of Ophthalmology, Semmelweis University, 1085, Mária u. 39, Budapest, Hungary;2. 3rd Department of Internal Medicine, Research Laboratory, Semmelweis University, 1125, Kútvölgyi út 4, Budapest, Hungary;1. Research Service, Veteran Affairs Western New York Healthcare System, 3495 Bailey Avenue, Buffalo, NY 14215, USA;2. Department of Ophthalmology, The State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Ross Eye Institute, 1176 Main Street, Buffalo, NY 14209, USA;3. SUNY Eye Institute, Buffalo, NY, USA
Abstract:
Keywords:corneal angiogenesis  dry eye  meibomian gland disease  meibomian gland dysfunction  ocular surface  pterygium  S100A proteins  RAGE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Receptor for advanced glycation endproducts  TLR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Toll-like receptor  IL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Interleukin  CK"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Cytokeratin  SCC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Squamous cell carcinoma  iTRAQ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Isobaric tagging for relative and absolute quantification  ORM1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  α1-acid glycoprotein 1  MMPs"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Matrix metalloproteinases  MAPK"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Mitogen-activated protein kinase  NFκ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0140"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Nuclear factor kappa  ROS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0150"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Reactive oxygen species  MGD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0160"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Meibomian gland dysfunction  PIP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0170"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Prolactin-inducible protein  UV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0180"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Ultraviolet  SELDI-TOF-MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0190"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry  HNP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0200"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Human neutrophil peptide  S-CorNV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0210"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Suture-induced corneal neovascularization  CB-CorNV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0220"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Chemical burn-induced corneal neovascularization  TNF-α"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0230"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Tumor necrosis factor-α  MIP-2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0240"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Macrophage inflammatory protein 2  VEGF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0250"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Vascular endothelial growth factor  TIRAP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0260"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Toll-interleukin 1 receptor domain-containing adaptor protein
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