脑梗死出血转化96例临床分析

目的：探讨脑梗死出血转化（HT）的病因,发生率,临床表现和影像学特点及预后。方法：对我院2002年1月至2008年7月96例脑梗死出血转化患者进行回顾性分析。结果：糖尿病、高血压、心房纤颤、血脂异常、大面积脑梗死是HT的主要病因,其发生率为20．3％,第一周为62．5％,第二周为31．2％,两周后为6．3％,其临床表现为头痛、呕吐、肢体无力加重、意识障碍加深,CT或MRI表现为非血肿型与血肿型,死亡率为16．7％。结论：对神经症状及体征加重的患者,尤其是大面积脑死患者,应及早查复查CT或MRI,有利于HT的早期诊治。

Clinical Analysis of 96 Patients with Hemorrhagic Transformation after Cerebral Infarction

Objective： To investigate the etiology, incidence, clinical manifestation, imaging features and prognosis of hemorrhagic transformation （HT） after cerebral infarction. Methods： Retrospective analysis was performed in 96 patients suffering from HT after cerebral infarction during January of 2002 and July of 2008 in Suining HHospital. Results： The main causes of HT were diabetes, hypertension, atrial fibrillation and massive cerebral infarction, and morbility was 20.3% ,and in the first week of infarction was 62.5% ,the second week 31.2% ,and after two weeks was 6.3%. Headache,vomiting,aggravated paralysis and conscious disturbance were the main appearances. CT and MRI scan demonstrated hemorrhagic or non-hemorrhagic type. Its mortality was 16.7 %. Conclusion： For the early diagnosis and therapy of HT,CT or MRI scan is necessary for the patients with aggravation clinical course.