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CEACAM-1 Induced CSF3-receptor Downregulation in Bone Marrow Associated With Refractory Neutropenia in Advanced Cirrhosis
Authors:Chhagan Bihari  Sukriti Baweja  Seggere Murlaikrishna Shasthry  Deepika Lal  Preeti Negi  Swati Thangariyal  Dinesh Mani Tripathi  Shiv Kumar Sarin
Affiliation:1.Department of Pathology and Hematology, Institute of Liver and Biliary Sciences, D1, Vasant Kunj, New Delhi, India;2.Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, D1, Vasant Kunj, New Delhi, India;3.Department of Hepatology, Institute of Liver and Biliary Sciences, D1, Vasant Kunj, New Delhi, India
Abstract:
Background and Aims: Cirrhosis patients exhibit cyto-penia, and, at times refractory neutropenia to granulocyte colony-stimulating factor (G-CSF), which acts th...
Keywords:Liver cirrhosis   Child-Turcott-Pugh score   Bone marrow   Granulocyte colony stimulating factor   CSF3R   CEACAM-1   Hematopoietic stem cells   Neutropenia
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