GyneFix IN IUD与MLCu IUD、γ-IUD临床效果比较

目的比较3种IUD的临床效果。方法对556例使用3种IUD的育龄妇女的使用效果、副反应进行临床对比研究,随访5年。结果GyneFixINIUD220例、MLCuIUD116例、γ-IUD220例。3种IUD5年带器妊娠率分别为3.49%、2.17%、4.56%,比较无显著性差异(P>0.05);脱落率分别为2.49%、13.66%、7.37%,比较有显著性差异(P<0.01);因症取出率分别为5.67%、6.78%、4.23%,比较无显著性差异(P>0.05);3个月以内异常出血发生率分别为34.5%、36.2%、23.1%,12个月分别为9.5%、16.3%、8.6%,比较有显著性差异(P<0.01)。结论GyneFixINIUD、γ-IUD具有脱落率低的优点,值得临床推广应用。

Comparative Study of GyneFix IN,MLCu and γ-IUDs

Objective: To study and compare the effect of three kinds of IUD. Methods:Effectiveness and side effects of three types of IUD inserted in 556 women were studied, and follow-up survey have persisted for five years. Results:There were 220 cases of GyneFix IN IUD, 116 cases of MLcuIUD and 220 cases of γ-IUD in 556 women. In five years, the rates of pregnancy in above three kinds of IUD were 3.49%,2.17% and 4.56%,respectively , and there was no significant difference amorg them.(P>0.05). The expulsion rates were 2.49%,13.66% and 7.37%,respectively,and were significantly different (P<0.001). The extraction rates because of some symptoms were 5.67%,6.78% and 4.23%,respectively,and were not significantly different(P>0.05). The incidence of abnormal bleeding was 34.5%,36.2% and 23.1% in three months and 9.5%,16.3% and 8.6% in twelve months, respectively, and were significantly different (P<0.001) . Conclusion: The GyneFixIN and γ-IUD have lower expulsion rate and are recommended to generalize in clinical application.