不同甲型肝炎疫苗免疫效果和应急接种适宜技术研究(一) 桦甸市829名4～10岁儿童抗HAV、HBsAg和ALT检测结果分析

目的对桦甸市829名儿童的抗HAV、HBsAg和ALT检测结果进行分析,从而确定健康人群。方法采用整群随机抽样的方法,对1～3年级学生和学前班儿童进行体检和问卷调查,选择既往无甲肝病史和甲肝疫苗接种史的人群作为研究对象,检测其血液中抗HAV、HBsAg和ALT的情况。结果通过对829名学生进行检测,3项均为正常者为710名。结论通过检测,确定了健康人群,为评价疫苗的安全性、免疫原性,比较儿童接种不同类型甲肝疫苗后不同时间抗体水平变化,以及应急接种方案确定了研究对象。

Immune effect of different hepatitis A vaccine and emergency vaccination of appropriate technology study(1) Analysis on the results of anti-HAV,HBsAg,and ALT of 829 children at age of 4 to 10 in Huadian city

Objective To analysis the testing results of anti-HAV,HBsAg and ALT of 829 children in Huadian city,consequently,made sure the healthy population.Method Adopting randomly chester sampling method,students of grade 1 to grade 3 and preschool children had physical examination and questionnaires,selecting the people with no previous hepatitis A history and no hepatitis A vaccination history as research objects,testing anti-HAV,HBsAg and ALT in their blood.Results Examined 829 children,in them,710 were normal.Co...