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Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers
Authors:Zhi‐Zhong Pan  Gaoyuan Wang  Shijuan Gao  Jiangxue Wu  Lili Dong  Yingchang Li  Yi Zhou  Wuying Du  Xiangqi Meng  Jinna Chen  Xinyuan Guan  Yulong He  Changchuan Pan  XF Steven Zheng  Xuemei Lu  Shuai Chen  Wenlin Huang
Affiliation:1. Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, PR China;2. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China;3. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China;4. Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China;5. Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, PR China;6. Medical Oncology, Sichuan Cancer Hospital and Institute, Second People's Hospital of Sichuan Province, Chengdu, PR China;7. Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA
Abstract:
Keywords:colorectal cancer  PCDHB3  gene mutation  tumor suppressor  prognostic marker
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