磁共振扩散加权成像在宫颈癌诊断中的应用

目的评价MR弥散加权成像(DWI)在宫颈癌诊断中应用的价值。方法对30例非宫颈肿瘤女性的子宫颈和50例宫颈癌患者的子宫颈进行常规MRI扫描和横断面DWI(b=600s/mm2),比较正常宫颈和宫颈癌病灶的表观弥散系数(apparent diffusion coefficient,ADC)值。结果正常子宫颈DWI表现为粘液,内、中、外带四层结构,其平均ADC值〔(1.71±0.14)×10-3 mm2/s)〕显著高于宫颈癌的ADC值〔(0.97±0.13)×10-3 mm2/s)〕(P<0.01)。结论 ADC值可有效地定量区分宫颈癌与正常宫颈,DWI更容易显示宫颈癌及其周围侵犯和盆腔淋巴结转移。

Application of diffusion weighted imaging in diagnosis of cervical cancer

Objective To estimate the value of diffusion weighted imaging in diagnosis of cervical carcinoma.Methods Routine MRI sequence and axial diffusion weighted sequence(b=600 s/mm2) were performed in 50 patients with cervical carcinoma and in 30 healthy women as control.The apparent diffusion coefficient(ADC) values of normal uterine cervix and cervical carcinoma were compared.Results Normal uterine cervix presented with 4 layers in DWI.The ADC value was significantly higher in normal uterine cervix than incervical carcinoma((1.51±0.16)×10-3 mm2 /s vs(0.98±0.11) ×10-3 mm2/s,P<0.01).Conclusion ADC value can be used to quantitatively discriminate cervical cancer from normal cervix and cervical secretion.DWI-MRI is easer than the conventional MRI sequences to reveal cervical carcinoma invasion and lymphatic metastasis.