多模式CT预测急性缺血性脑卒中出血转化风险的研究进展

出血转化是急性缺血性脑卒中自然转归过程之一，也可发生在溶栓或抗凝药物治疗之后。血脑屏障破坏、缺血再灌注、侧支循环的建立等与之密切相关。早期预测急性缺血性脑卒中出血转化风险对其治疗方案的选择及预后具有重要意义。CT平扫、CT灌注成像及CT血管成像检查对于出血转化高风险人群的检出具有较大价值。就多模式CT参数及其阈值预测出血转化的研究进展予以综述。

Research progress of multimode CT in predicting hemorrhagic transformation risk in acute ischemic stroke

Hemorrhagic transformation is one of the natural prognosis of acute ischemic stroke, and can also occur after thrombolytic or anticoagulant therapy. Blood brain barrier disruption, ischemia reperfusion, and collateral circulation are closely related to hemorrhagic transformation. Early prediction of the risk of hemorrhagic transformation in acute ischemic stroke is of great significance to the choice of treatment and prognosis. Non-contrast CT, CT perfusion, and CT angiography are of great value in the detection of high risk groups of hemorrhagic transformation. In this article, we reviewed the progress of multimode CT parameters and thresholds in predicting hemorrhagic transformation.