Aminoacetylenic carbonyl compounds |
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| Authors: | A. K. Aren A. Kh. Zitsmanis S. K. Germane Ya. V. Ozolin'sh |
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| Affiliation: | (1) Riga Polytechnic Institute, USSR;(2) Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR, Riga |
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| Abstract: | ![]()
Conclusion 2-Substituted 2-propargylindan-1,3-diones were prepared by treating the salt of 2-substituted 1,3-indandione with propargyl bromide. Aminomethylation of the product with paraformaldehyde and secondary amines afforded a series of 2-substituted 2-( -aminobutynyl)indan-1,3-diones which exhibit depressant effects on the central nervous system.Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 8, pp. 18–22, August, 1968. |
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