一种诊断结直肠癌患者淋巴结转移的新方法

结直肠癌的预后判断主要根据有确切资料的病理学分期、原发灶浸润深度、分化程度和微血管侵犯的组织学结果,术后3～7 d就能得出结果.但传统的淋巴结检查方法中,淋巴结转移数目和转移淋巴结解剖部位结果常因工作量巨大,旷日持久,不能得出结果.结直肠癌患者术后医患双方都要求及早确定分期,用以确定辅助化疗,治疗过度或治疗不足皆对病人有害,是无证据、不负责且不规范的治疗.当今国外有研究局部淋巴结转移与淋巴结浸出液癌胚抗原(carcinoembryonic,CEA)浓度密切相关,并能简捷、快速得出结果,有待成为一种诊断结直肠癌淋巴结转移的新方法.

A new method in the diagnosis of lymphnode metastasis in patients with colorectal cancer

Forecasting the colorectal cancer prognosis mainly based on the accurate pathological stages,the primary carcinoma infiltrated depth,the cell differentiation degree and the capillaries infiltrated in histology result,and the outcome can be obtained latter 3-7 days after the opemtion.But in traditional lymph node inspection method,identifying the quantity and the anatomy locality of metastasized lymph node normally costs long time,sometimes cannot obtain the result.M addition,to identify the stage of the cancer is a key point to determine the assistant chemotherapy is useful or not,for both doctor and patient,because the excessive treatment and the insufficient treatment are both harmful to the patient.Now overseas has an abvoad study showes that regional lymph node metastasis have something to do with the concentration of(Carcinembryonic,CEA)in the lymph node.The CEA concentration can be obtained simply and directly.So,testing the CEA concentration in lymph node may become a new method in the diagnosis of lymph node metastasis for patients with colorectal cancer.