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蓝芩口服液絮凝澄清工艺研究
引用本文:李赛荣,曹玉明,卜令斌. 蓝芩口服液絮凝澄清工艺研究[J]. 中国药业, 2005, 14(2): 51-52
作者姓名:李赛荣  曹玉明  卜令斌
作者单位:扬子江药业集团有限公司,江苏,泰州,225321
摘    要:目的:探讨壳聚糖絮凝法代替乙醇沉淀法用于蓝芩口服液制备的可行性.方法:考察壳聚糖絮凝法的沉淀效果、过滤难易及对栀子苷含量的影响.结果:壳聚糖絮凝法与醇沉法同样能使药液澄清,且对栀子苷的含量影响较小,可缩短生产周期,降低成本.结论:壳聚糖絮凝法可代替乙醇沉淀法用于蓝芩口服液的澄清工艺.

关 键 词:蓝芩口服液  壳聚糖絮凝剂  澄清工艺
文章编号:1006-4931(2005)02-0051-02
修稿时间:2004-05-09

Study on Clarification Process of Lanqin Oral Liquid by Chitosan
Li Sairong,Cao Yuming,Bu Linbin. Study on Clarification Process of Lanqin Oral Liquid by Chitosan[J]. China Pharmaceuticals, 2005, 14(2): 51-52
Authors:Li Sairong  Cao Yuming  Bu Linbin
Abstract:Objective:To study the feasibility of clarification procedure on Lanqin oral solution using chitosan instead of alcohol.Methods:Using chitosan clarifier with different concentration to the clarification procedure of Lanqin oral solution.The clarification,filtrate and the content of gardenia glycoside were compared with that of ethanol subsiding.Results:Chitosan clarifier could make the solution clarificant as alcohol.On the retaining of gardenia glycoside there was no differences between this procedure and the former.The period of production and cost can be reduced.Conclusion:Chitosan can be used to the clarification procedure of Lanqin oral solution instead of alcohol.
Keywords:Lanqin oral solution  chitosan  clarification process
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