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BRONCHIOLO-ALVEOLAR ADENOCARCINOMA WITH MULTIPLE CYSTS
Authors:Shunsuke Imai    Susumu Sekigawa    Hiroaki Yamamoto    Yoshihiko Tsubura    Michiyo Miyanaga  Nobuhiro Narita  Riichiro Mikami
Affiliation:Department of Pathology, Nara Medical University, Kashihara-shi;Department of Internal Medicine Nara Medical University, Kashihara-shi
Abstract:An autopsy case of bronchiolo-alveolar adenocarcinoma in the lung is reported. The patient is a 70-year-old male who complained of severe cough with 500–600 ml watery sputum a day, loss of weight, and general fatigue. Autopsy revealed numerous whitish tumors in various sizes with multiple cysts in both lungs, with no metastasis being found in any other organs. Histological findings identified the tumor as a bronchiolo-alveolar adenocarcinoma originating from the lungs. Electron-microscopic findings showed that the tumor cells were covered by prominent microvilli, and contained abundant irregulary-shaped cytoplasmic vacuoles suggestive of mucin.
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