中药润目灵治疗水样液缺乏性干眼症的临床疗效

目的:观察中药润目灵治疗水样液缺乏性干眼症的临床疗效。方法:水样液缺乏性干眼症121例分为润目灵(49例),必嗽平(24例),泪然(48例)3组。疗程均为4wk。结果:润目灵与必嗽平相比较,对增加泪流量、改善角膜染色作用无统计学差异,润目灵对泪膜破裂时间、眼部症状改善优于必嗽平,统计学上有意义(P<0.05);润目灵对增加泪流量、延长泪膜破裂时间、改善眼部症状优于泪然,统计学上有显著意义(P<0.01)。结论:润目灵有促进泪液分泌、延长泪膜破裂时间和促进角膜病变修复的作用,对水样液缺乏性干眼症有明显的治疗作用。

Effect of runmuling on aqueous tear deficiency xeroma

AIM:To investigate the effect of runmuling aqueous tear deficiency(ATD) xeroma.·METHODS:One hundred and twenty-one patients with ATD were dividied into runmuling group(49 cases),bromhexine group(24 cases) and tear naturals Ⅱ(TN-Ⅱ) group(48 cases) randomly.The patients were treated for one month in three groups.·RESULTS:There were no significant differences between runmuling group and bromhexine group in increasing tear flows and improving the cornea dyeing effect(P>0.05),but the difference in stain of cornea by fluorescein,break-up time of tear film and eye symptom was statistically significant between the two groups(P<0.05).Runmuling was better than TN-II in increasing tear flows and improving eye symptom,and the difference was statistically significant between runmuling group and TN-Ⅱ group(P<0.01).·CONCLUSION:Runmuling can promote lacrimal secretion,lengthening break-up time of tear film and promote keratopathy plerosis and has therapeutical effect on ATD xeroma.