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香加皮有效部位滴丸的质量标准研究
引用本文:杨虹,刘虹,王萌,任晓亮,朱晓月. 香加皮有效部位滴丸的质量标准研究[J]. 天津中医药大学学报, 2011, 28(4): 332-334
作者姓名:杨虹  刘虹  王萌  任晓亮  朱晓月
作者单位:天津中医药大学科研处, 天津, 300193;天津中医药大学中医药研究院, 教育部方剂学重点实验室, 天津, 300193;天津中医药大学中医药研究院, 教育部方剂学重点实验室, 天津, 300193;天津中医药大学中医药研究院, 教育部方剂学重点实验室, 天津, 300193;天津中医药大学中医药研究院, 教育部方剂学重点实验室, 天津, 300193
基金项目:国家科技支撑计划“重大新药创制”重大专项(2009ZX09103-372)
摘    要:[目的]建立香加皮有效部位滴丸的质量标准。[方法]建立了高效液相色谱(HPLC)法进行杠柳毒苷含量测定和杠柳毒苷的均匀度检查;对滴丸剂进行了常温下的初步稳定性考察。[结果]香加皮有效部位滴丸含量测定方法学考察的指标均符合有关规定;滴丸均匀度符合要求。[结论]建立了有效部位及滴丸的质量标准,方法简便、可靠。滴丸剂质量基本稳定。

关 键 词:香加皮  有效部位  滴丸  质量标准  杠柳毒苷
收稿时间:2011-04-25

Study on quality standard of effective fraction drop pills in Cortex Periplocae
YANG Hong,LIU Hong,WANG Meng. Study on quality standard of effective fraction drop pills in Cortex Periplocae[J]. Journal of Tianjin University of Traditonal Chinese Medicine, 2011, 28(4): 332-334
Authors:YANG Hong  LIU Hong  WANG Meng
Affiliation:Management office of scientific research of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Research institute of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Research institute of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Research institute of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Research institute of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:[Objective] To establish quality standard of effective fraction drop pills for anti-heart failure in Cortex Periplocae.[Methods] HPLC method was adopted for content determination of periplocin and content uniformity in drop pills.The primary study was made on the stability of drop pills under the room temperature.[Results] The methodology of content determination for the drop pills and the uniformity complied with rules.[Conclusion] The quality standard of the effective fraction drop pills for anti-heart failure in Cortex Periplocae was set up and the method was convenient and reproducible.The drop pills were relatively stable.
Keywords:Cortex Periplocae  effective fraction  drop pills  quality standard  periplocin
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