中西医结合联合治疗慢性阻塞性肺疾病急性加重期的临床研究

目的观察中西医结合联合治疗慢性阻塞性肺疾病急性加重（AECOPD）的临床疗效。方法选取AECOPD患者90例，随机分为治疗组和对照组，分别为45例，对照组给予抗感染、解痉平喘、纠正内环境紊乱等西医常规治疗。治疗组在对照组常规治疗的基础上，采用清金化痰汤加减治疗，每日1剂。观察两组治疗后临床疗效、住院时间、血气分析及肺功能变化等。结果治疗组有效率明显高于对照组，治疗组住院时间较对照组时间明显缩短，均有明显统计学意义（P〈0．05）。两组治疗后FEV1/FVC、PaCO2、pH等无明显差异。治疗组治疗后PaO2、FVC、FEV1／预计值明显好转，较对照组治疗后差异有统计学意义（P〈0．05）。结论中西医结合联合治疗AECOPD，可明显提高临床有效率、改善肺功能等，明显优于单纯西医常规治疗。

Clinical Study of Combined Treatment of Traditional Chinese and Western Medicine for Acute Exacerbations in Chronic Obstructive Pulmonary Disease

Objective： To evaluate the efficacy of combined treatment of traditional Chinese and western medicine in treating acute exacerbations in chronic obstructive pulmonary disease. Methods： 90 patients with acute exacerbations in chronic obstructive pulmonary disease （AECOPD） were randomly divided into two groups which had 45 patients. The blank group with AECOPD were treated with conventional western medicine.The pa- tients in combined treatment group were treated by both conventional western medicine and traditional Chinese medicine .The clinical symptoms,the length of hospital stay,the lung function and the blood gas analysis should be observed and tested in two groups. Results： The effective rate in combined treatment group was obviously higher than that in blank group （P 〈 0.05）. The length of hospital stay in combined treatment group was shorter than that in blank group （P〈 0.05）.Alveolar oxygen partial pressure （PaO2）, puhnonary function index forced vital capacity（FVC）, 1 s percentage of forced expiratory volume （FEV1/predicted%） in combined treatment group were significantly improved. There were some statistical differences between 2 groups （P〈 0.05）. Conclusion： Combined treatment can effectively improve the symptoms, pulmonary function in the patients with acute exacerbation of chronic obstructive pulmonary disease. Its effect is superior to that in the conventional western medicine.