Neuropeptide immunoreactivity of pericellular baskets in the guinea pig trigeminal ganglion

Using immunohistochemical techniques, calcitonin gene-related peptide, substance P and cholecystokinin localize to baskets of fine nerve fibers that completely surround occasional neurons in the guinea pig trigeminal ganglion. These observations, viewed with prior neuroanatomical studies indicating an intrinsic origin for these structures, raise again the possibility of intraganglionic communication within the trigeminal ganglion.