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急性白血病并发播散性热带念珠菌血症的临床分析
引用本文:孙璇,张新友,陈庆奇,徐肇明,姜容,林海清. 急性白血病并发播散性热带念珠菌血症的临床分析[J]. 肿瘤学杂志, 2009, 15(11)
作者姓名:孙璇  张新友  陈庆奇  徐肇明  姜容  林海清
作者单位:深圳市人民医院,广东,深圳,518020
摘    要:
[目的]提高对急性白血病(AL)并发播散性热带念珠菌血症临床特征的认识。[方法]回顾性分析3例AL并发播散性热带念珠菌血症临床表现、诊治过程和转归。[结果]在3例患者中,中性粒细胞(ANC)缺乏时出现持续发热、鹅口疮;B超均发现肝内类圆形或椭圆形多发低回声,血培养均示热带念珠菌生长。3例患者采用两性霉素B(AmpB)联合5氟胞嘧啶治疗后体温正常。[结论]AL并发播散性热带念珠菌血症的诊断需结合病史、临床表现、实验室检查及影像学检查综合判断;选用两性霉素B联合5氟胞嘧啶治疗有较好的临床疗效。

关 键 词:白血病  急性  热带念珠菌  真菌血症

A Clinical Study of Disseminated Candida Tropicalis Fungemia in Patients with Acute Leukemia
Affiliation:SUN Xuan; ZHANG Xin-you; CHEN Qing-qi; et al. (Shenzhen People’s Hospital; Shenzhen 518020; China);
Abstract:
[Purpose] To improve the recognition of clinical characteristics of disseminated Candida tropicalis fungemia in patients with acute leukemia(AL). [Methods] Clinical manifestations, diagnosis, treatment and prognosis were retrospectively investigated in 3 cases of AL patients with disseminated Candida tropicalis fungemia. [Results] Of 3 cases, persistent fever and thrush occured during the time of agranulocytosis, spherical-like or oval multiple low-level echoes were detected in liver under type-B ultrasonic...
Keywords:leukemia  acute  candidiasis  fungemia
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