走罐联合消疕2号方治疗血瘀型斑块状银屑病临床疗效及对相关细胞因子的影响

目的 观察走罐疗法联合消疕2号方治疗血瘀证斑块状银屑病的有效性、安全性及对辅助性T细胞(Th17)细胞因子的影响.方法 60例斑块状银屑病(血瘀证)患者作为研究对象,随机分为治疗组30例和对照组30例.对照组内服消疕2号方治疗,治疗组在对照组的基础上加用走罐疗法.比较2组患者治疗前后银屑病皮损面积及严重程度指数(PAS...

Clinical Observation of Moving Cupping Combined with Xiaobi Erhao Fang on Blood Stasis Plaque Psoriasis and Its Effects on Related Cytokines

Objective In order to observe the therapeutic effects of walking cupping therapy combined with Xiaobi Erhao Fang on plaque psoriasis(blood stasis syndrome)and its security and effects on Th17 cell-related cytokines.Methods Sixty patients with plaque psoriasis(blood stasis syndrome)were taken as the research objects and randomly divided into treatment group with 30 cases and control group with 30 cases.The control group was treated with Xiaobi Erhao Fang,and the treatment group was treated with moving cupping therapy on the basis of the control group.The psoriasis area and severity index(PASI),the total effective rate,the levels of serum interleukin-17(IL-17),IL-22 and IL-23 before and after treatment of the two groups were compared.Results The total effective rate of the treatment group after treatment was higher than that of the control group(P<0.05),and the PASI score of the treatment group was significantly lower than that of the control group(P<0.05),the differences were statistically significant.Before treatment,the serum levels of IL-17,IL-22 and IL-23 in the treatment group and the control group were significantly higher than those in the healthy control group(P<0.05).The serum IL-17,IL-22 and IL-23 levels of the treatment group and the control group decreased at the third and sixth week,and the treatment group was significantly lower than the control group(P<0.05),and the differences were statistically significant.Conclusion Moving cupping therapy combined with Xiaobi Erhao Fang in the treatment of plaque psoriasis is safe and effective.