肌骨超声在诊断ICU获得性肌无力中的研究进展

ICU获得性肌无力（ICU-AW）是重症患者常见的并发症，目前的诊断主要依据医学研究委员会积分量表(MRC)进行，但早期往往难以在ICU中实施。多项研究已经证实肌骨超声可以早期发现重症患者肌肉体积的下降和结构的改变，同肌肉功能具有一定的相关性。本文从上肢肌肉、膈肌、下肢肌肉分别阐述了目前使用肌骨超声检测相关肌肉指标来诊断ICU-AW的研究进展，发现由于研究样本少和重复性实验少，各个实验结果往往相互矛盾，无法得到一个较为准确的结论，仅有股直肌横截面积（CSA）和回声强度的变化同MRC评分之间存在中度相关性，且具有统计学意义。未来需要更多的大样本、重复性实验来深入研究这个问题。

Research Progress of Musculoskeletal Ultrasound in Diagnosis of Intensive Care Unit-Acquired Weakness

Intensive care unit acquired weakness (ICU-AW) is a common complication in patients admitted to the intensive care unit(ICU). Traditionally, ICU-AW is diagnosed by assessment of manual muscle strength, using the Medical Research Council (MRC) score, but it is difficult to perform in the ICU setting. Recent studies demonstrated that musculoskeletal ultrasound can detect the decrease in muscle volume and structural changes in critical patients at an early stage, which has a certain correlation with muscle function.This paper describs the current research progress of using musculoskeletal ultrasound to detect upper extremity muscles, diaphragm and lower extremity muscles to diagnose ICU-AW. We found that due to the small samples and few repeated experiments, the results of each experiment are often contradictory and a more accurate conclusion could not be obtained.Only changes in rectus femoris cross-sectional area (CSA) and echointensity have a moderate correlation with MRC score, which was statistically significant.In the future, more large-sample, repeatable experiments are needed to further investigate this question.