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间歇性气压治疗促进跟腱愈合的实验研究
引用本文:陈佳,虞和君.间歇性气压治疗促进跟腱愈合的实验研究[J].全科医学临床与教育,2011,9(5):494-496.
作者姓名:陈佳  虞和君
作者单位:1. 杭州市下沙医院骨科,浙江杭州,310018
2. 浙江大学医学院附属邵逸夫医院骨科
摘    要:目的 探讨间歇性气压治疗促进跟腱断裂修复的疗效.方法 实验分间歇性气压治疗组和未治疗组,建立大鼠跟腱断裂模型后,通过分析比较两组大鼠跟腱愈合横截面积、成纤维细胞计数、糖胺聚糖染色比例及一氧化氮合酶含量等指标评估治疗疗效及跟腱修复机制.结果 3周后跟腱愈合横截面积治疗组为(0.93±0.15)mm2,未治疗组为(0.65±0.06)mm2;光镜下成纤维细胞计数治疗组为(51.23±4.52)个,未治疗组为(30.87±9.87)个;Ⅲ型胶原染色比例治疗组为(12.82±1.89)%,未治疗组为(10.00±0.78)%;糖胺聚糖染色比例治疗组为(89.28±2.35)%,未治疗组为(67.48±5.49)%,一氧化氮合酶蛋白含量治疗组为(217.75±8.78)AU,未治疗组为(170.00±9.54)AU;两组各项结果比较,差异均有统计学意义(t分别=1.58、1.63、1.78、1.81、1.66,P均<0.05).结论 间歇性气压治疗能够有效增加Ⅲ型胶原及糖胺聚糖的表达,增加跟腱愈合横截面积,促进肌腱愈合.

关 键 词:跟腱损伤  气压治疗  物理治疗

Intermittent air pressure therapy to promote healing of achilles tendon
CHEN Jia,YU Hejun.Intermittent air pressure therapy to promote healing of achilles tendon[J].clinical education of general practice,2011,9(5):494-496.
Authors:CHEN Jia  YU Hejun
Institution:CHEN Jia,YU Hejun.Department of Orthopaedics,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,China
Abstract:Objective To develop a simple physical therapy,intermittent air pressure treatment,to promote tendon healing process.Methods The mice tendon rupture model was generated by dissection the achilles tendon,followed by suture at the same time.After the operation,the mice were treated with or without intermittent air pressure for 3 weeks.The healed tendon cross -sectional area and the number of fibroblasts were measured.The alignment of the collagen fiber was observed under polarized light microscope,with the pe...
Keywords:achilles tendon injury  pressure treatment  physical therapy  
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