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| 阿维A胶囊对晚期非小细胞肺癌的诱导分化治疗的疗效分析 | |
| 引用本文： | 刘震天. 阿维A胶囊对晚期非小细胞肺癌的诱导分化治疗的疗效分析[J]. 现代预防医学, 2011, 38(19): 4070-4071,4073 |
| 作者姓名： | 刘震天 |
| 作者单位： | 江西省肿瘤医院内二科,南昌,330029 |
| 摘 要： | [目的]探讨阿维A胶囊对晚期非小细胞肺癌的诱导分化治疗的疗效。[方法]选择某院诊治的晚期非小细胞肺癌患者47例,根据随机原则分为观察组(24例)和对照组(23例)。观察组患者采用顺铂+阿维A胶囊方案,对照组患者仅应用顺铂方案,两组患者均坚持两个周期以上的化疗。比较两组患者治疗效果及不良反应发生情况,测量并比较治疗前后两组患者血癌胚抗原(CEA)、神经特异烯醇化酶(NSE)及非小细胞相关抗原(CYFRA21-1)水平。[结果]①观察组患者治疗有效率、疾病控制率高于对照组,但均无统计学意义(P﹥0.05)。②治疗后,观察组患者血CEA、NSE及CYFRA21-1水平明显低于治疗前(P﹤0.05)。对照组中,仅CYFRA21-1的水平有显著降低(P﹤0.05)。观察组患者血CEA及CYFRA21-1水平明显低于对照组(P﹤0.05)。③观察组与对照组不良反应的发生率间差异无统计学意义(P﹥0.05)。[结论]阿维A胶囊能够显著降低晚期非小细胞肺癌血清肿瘤标记物水平,并能在一定程度上提高疗效。 |
| 关 键 词： | 阿维A 非小细胞肺癌 治疗 |
THE CLINICAL ANALYSIS OF AVI A CAPSULE IN THE INDUCED DIFFERENTIATION THERAPY OF ADVANCED NON-SMALL CELL LUNG CANCER |
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| LIU Zhen-tian. THE CLINICAL ANALYSIS OF AVI A CAPSULE IN THE INDUCED DIFFERENTIATION THERAPY OF ADVANCED NON-SMALL CELL LUNG CANCER[J]. Modern Preventive Medicine, 2011, 38(19): 4070-4071,4073 | |
| Authors: | LIU Zhen-tian |
| Affiliation: | LIU Zhen-tian.(Department of Internal Medicine,the Tumor Hospital of Jiangxi Province,Nanchang 330029,China) |
| Abstract: | [Objective]To investigate the effect of Avi A capsule in the induced differentiation therapy of advanced non-small cell lung cancer.[Methods]47 non-small cell lung cancer patients treated in our hospital were chosen,they were randomly divided into the observation group(24 cases)and the control group(23 cases).Observation group was treated with cisplatin + Avi A capsule program,while the control group was treated with cisplatin alone.All patients were treated with two cycles of chemotherapy.Patients' outcome... |
| Keywords: | Avi A Non-small cell lung cancer Treatment |
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