豚鼠去大脑僵直后畸变产物耳声发射变化的实验观察

目的：进一步确定皮层高级中枢是否对耳蜗主动微机制有调控作用。方法：观察１７只豚鼠在去大脑僵直前、后的畸变产物耳声发射（ＯＰＯＡＥｓ）变化情况。结果：在避免体温和颅温下降、缺氧等情况下，豚鼠去大脑僵直后２ｍｉｎ，５ｍｉｎ，１０ｍｉｎ的ＤＰＯＡＥｓ幅值显著下降，３０ｍｉｎ开始逐渐恢复，６０ｍｉｎ基本恢复到术前水平。结论：结果 提示大脑皮层高级中枢对耳蜗主动微机制有下行调控作用，文中对可能的机制进行了讨

DPOAEs amplitude decline after decerebration in guinea pigs

Objective:To further prove whether auditory cortex topdown efferent exists and observe its effect on outer hair cells (OHCs). Methods:Distortion product otoacoustic emissions (DPOAEs) were measured before and after decerebration in 17 guinea pigs. Results:DPOAEs amplitude decreased significantly and rapidly after decerebration and remained at the lowest levels for 2,5,10 min. DPOAEs gradually recovered to the previous levels with time delay. Conclusion:It was further demonstrated that auditory cortex efferent really exists and controls OHCs and DPOAEs via medial olivocochlear system (MOCS). The possible mechanism was discussed in the paper.