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| "泻剂结肠"大鼠的结肠肌电生理变化及其意义 | |
| 引用本文： | 黄显凯,胥基太,童卫东. "泻剂结肠"大鼠的结肠肌电生理变化及其意义[J]. 中国普外基础与临床杂志, 2003, 10(1): 28-29,32 |
| 作者姓名： | 黄显凯 胥基太 童卫东 |
| 作者单位： | 第三军医大学大坪医院普外科,重庆,400042 |
| 摘 要： | 目的 探讨慢性输型便秘（STC）的发生机理。方法 建立大鼠“泻剂结肠”模型,并测定其结肠的肌电生理活动变化。结果 “泻剂结肠”大鼠的结肠慢波频率减慢,振幅降低;餐后峰电位发放明显少于正常对照组且持续时间短,表明胃结肠反射明显减弱。结论 该研究结果提示,长期服用接触性泻剂对结肠肠神经系统有损害作用,这在STC的发生机理中可能具有重要意义。 |
| 关 键 词： | 慢传输型便秘 泻剂结肠 胃肠肌电 |
| 文章编号： | 1007-9424(2003)01-0028-02 |
The Change of Electromyophysiology of the Rat with Cathartic Colon |
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| HUANG Xian kai,XU Ji tai,TONG Wei dong. The Change of Electromyophysiology of the Rat with Cathartic Colon[J]. Chinese Journal of Bases and Clinics In General Surgery, 2003, 10(1): 28-29,32 | |
| Authors: | HUANG Xian kai XU Ji tai TONG Wei dong |
| Affiliation: | HUANG Xian kai,XU Ji tai,TONG Wei dong.Department of General Surgery,Daping Hospital,The Third Military Medical University,Chongqing 400042,China |
| Abstract: | Objective To explore etiopathogenesis of slow transit constipation(STC). Methods The model of rat with "cathartic colon" was established, and the changes of colonic electromyography of the rat was examined. Results The frequency and amplitude of slow wave in vivo of rats with cathartic colon was decreased markedly. Postmeal spike potential and duration was decreased, showing that gastrocolonic reflex of rats colon was decreased.Conclusion Long term abuse of stimulant laxuatives could damage enteric nervous system and accelerate the pathological changes of STC. |
| Keywords: | Slow transit constipation Cathartic colon Gastrointestinal electrophysiology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |