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| 组织水肿的一个力学模型及生理分析 | |
| 引用本文： | 姚伟,丁光宏,沈雪勇,戴建华,程珂,陈尔瑜,党瑞山,魏瑚.组织水肿的一个力学模型及生理分析[J].生物医学工程学杂志,2005,22(1):15-19. |
| 作者姓名： | 姚伟 丁光宏 沈雪勇 戴建华 程珂 陈尔瑜 党瑞山 魏瑚 |
| 作者单位： | 1. 复旦大学,力学与工程科学系,上海,200433 2. 上海中医药大学,针灸推拿学院,上海,200032 3. 中国人民解放军第二军医大学,解剖教研室,上海,200433 4. 上海市针灸经络研究中心,上海,200032 |
| 基金项目： | 国家自然科学基金资助项目 (10 14 2 0 0 2 )，上海市教委重点学科 (第 4期 )资助 |
| 摘 要： | 水肿是一种常见的生理现象 ,但其发生发展机理尚未得到合理的解释 ,我们根据组织液压力对其结构的影响和血液、组织液物质交换理论 ,建立一种描述水肿发生和发展的力学模型。模型的理论计算结果显示物质交换动态平衡的破坏所产生的组织液压和组织结构的变化将引发水肿 ,这与临床的实验发现一致 ,水肿形成机理的讨论指出水肿治疗的关键在组织结构破坏前调整血浆与组织液间物质交换的不平衡。 |
| 关 键 词： | 组织水肿 离解能 集中参数模型 胶体渗透压 |
| 收稿时间： | 2003-01-15 |
| 修稿时间： | 2003-01-152003-05-19 |
A Dynamics Model Describing Edema and Its Physiological Analysis |
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| Wei Yao,Guanghong Ding,Xueyong Shen,Jianhua Dai,Ke Cheng,Er''yu Chen,Ruishang Dang,Hu Wei.A Dynamics Model Describing Edema and Its Physiological Analysis[J].Journal of Biomedical Engineering,2005,22(1):15-19. | |
| Authors: | Wei Yao Guanghong Ding Xueyong Shen Jianhua Dai Ke Cheng Er'yu Chen Ruishang Dang Hu Wei |
| Institution: | 1. Department of Mechanics, Fudan University, Shanghai 200433,China; 2. Acupuncture Department of Shanghai University of Traditional Chinese Medicine, Shanghai 200032,China; 3. Anatomy Department of the Second Medical University of PLA, Shanghai 200433,China; 4.Shanghai Research Center of Acupuncture and Meridian, Shanghai 200032,China |
| Abstract: | Edema is a common pathological symptom, but its development mechanism is unknown. Based on the bearings of pressure upon interstitium structure and substantial exchange between plasma and interstitial fluid, a dymamics model describing the development of edema was set up. The model's theoretical results showed that the variations of interstitium pressure and structure due to imbalance of substantial exchange may lead to the development of edema, which is in accordance with recent clinical researches. Discussions on the dynamic mechanism of the development of edema proposed that the best way to prevent edema is instituting treatment before the interstitial structure being destroyed. |
| Keywords: | Edema Dissociation energy Lumped parameter model Colloid osmosis pressure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |