| 白术微型饮片制备工艺优化研究 |
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| 引用本文： | 单国顺,赵启苗,项欣欣,吴青华,贾天柱.白术微型饮片制备工艺优化研究[J].中华中医药学刊,2021(2). |
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| 作者姓名： | 单国顺 赵启苗 项欣欣 吴青华 贾天柱 |
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| 作者单位： | 辽宁中医药大学药学院;辽宁中医药大学杏林学院;国药控股营口有限公司 |
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| 基金项目： | 国家自然科学基金青年科学基金(81803726);国家中医药管理局中药炮制技术传承基地项目(国中医药科技[2015]86号);辽宁省自然科学基金(20170540596);辽宁省自然科学基金博士启动项目(20180540012)。 |
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| 摘 要： | 目的对白术微型饮片的制备工艺进行优化。方法采用正交试验的方法,选取饮片的成品率、煎膏率、流动时间及白术内酯Ⅰ、Ⅱ、Ⅲ的煎出率为考察指标,以饮片的切制方式、切制粒径以及干燥的温度为考察因素。结果白术药材以横切结合纵切的方式,切制成粒径为0.3~0.4 mm3的小丁块,并于60℃条件下烘干,其流动性及煎出率均可得到显著提高。结论白术微型饮片制备工艺合理可行,有利于饮片自动调剂及煎煮设备的发展。
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| 关 键 词： | 白术 微型饮片 工艺 正交试验 |
Optimization on Preparation Process of Micro Slices of Baizhu(Atractylodes macrocephala Koidz.) |
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| SHAN Guoshun,ZHAO Qimiao,XIANG Xinxin,WU Qinghua,JIA Tianzhu.Optimization on Preparation Process of Micro Slices of Baizhu(Atractylodes macrocephala Koidz.)[J].Chinese Archives of Traditional Chinese Medicine,2021(2). |
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| Authors: | SHAN Guoshun ZHAO Qimiao XIANG Xinxin WU Qinghua JIA Tianzhu |
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| Institution: | (College of Pharmacy,Liaoning University of Traditional Chinese Medicine,Dalian 116600,Liaoning,China;College of Xinglin,Liaoning University of Traditional Chinese Medicine,Shenyang 110167,Liaoning,China;Sinopharm Holding Yingkou Co.,Ltd,Yingkou 115000,Liaoning,China) |
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| Abstract: | Objective To optimize the preparation process of micro slices of Baizhu(Atractylodes macrocephala Koidz.).Method The orthogonal design was used which selected the score of yield,flow time and decocting rate of AtractylenolideⅠ,Ⅱ,Ⅲas examining index and cutting mode,partical size and drying temperature for investigation factors.Results The best cutting process of Baizhu(Atractylodes macrocephala Koidz.)was as following:crude drug was cutting in the mode of crosscut combined with length cutting,partical size was 0.3-0.4 mm3and drying temperature was 60℃.Conclusion The optimal cutting technology of Baizhu(Atractylodes macrocephala Koidz.)was reasonable and feasible.It was also favor to the development of automatic dispensing and decocting equipment. |
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| Keywords: | Baizhu(Atractylodes macrocephala Koidz ) micro slices processing orthogonal design |
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