Comparative efficacy of platidiam and carboplatin against tumor cells of human ovarian primary carcinomas

The efficacies of platidiam and carboplatin against human ovarian cancer cells (21 samples) were compared usingthe in vitro MTT test. Sampling analysis showed a some-what higher mean activity of carboplatin in comparison with platidiam in the dose range equivalent to 0.1 to 3.0 therapeutic doses. The efficacy of carboplatin was found to increase more rapidly with dosage build-up than that of platidiam. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No. 8, pp. 208–210, August, 1995