进行肝移植蛋白质组学研究可行性探讨

随着肝移植技术的日臻完善,相关的基础研究亦逐步深入,但诸如缺血再灌注损伤的问题至今尚在探讨中。蛋白质组学是上世纪90年代中期国际上诞生的一门新兴学科,是后基因组时代生命科学研究的核心内容之一。肝移植的蛋白质组学研究在国内尚无报道,国外报道亦较少。本文兹就有关国外肝移植领域的蛋白质组学研究现况作一综述,为蛋白质组学在肝移植中的应用热点问题提供新的研究思路。

Discussion on the feasibility of proteomic research in liver transplantation

With the development of liver transplantation throughout the world,corresponded basic researches have advanced progressively,but some of many critical problems such as ischemia reperfusion injury remain unclear.Proteomics is a new subject first known in the middle of 1990's and core content at the era of post-genomics.So far there are few studies related to proteomics in liver transplantation.We introduce the progression of this new field and propose that proteomics may be a key to the problems mentioned above.