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SEN病毒研究
引用本文:帅金志,白旭华. SEN病毒研究[J]. 医学综述, 2007, 13(15): 1143-1144
作者姓名:帅金志  白旭华
作者单位:石河子大学新疆地方与民族高发病省部共建教育部重点实验室,新疆,石河子,832002
摘    要:
SEN病毒是从1例人类免疫缺陷病毒患者血清中分离出的一种无包膜、单链、环状DNA病毒,属圆环病毒科,基因组全长约为3900个核苷酸,共有SENVA~H8种亚型,至少有3个开放读码框架。研究显示该病毒与输血相关性非甲~非戊型肝炎有强相关性,该病毒可单独感染,也可与乙型肝炎、丙型肝炎、肝细胞癌等混合感染。目前,SEN病毒作为不明原因肝炎的致病因子尚缺乏有力的证据。

关 键 词:SEN病毒  肝炎  传播途径  致病性
文章编号:1006-2084(2007)15-1143-02
修稿时间:2006-10-24

Research Progress of SEN Virus
SHUAI Jin-zhi,BAI Xu-hua. Research Progress of SEN Virus[J]. Medical Recapitulate, 2007, 13(15): 1143-1144
Authors:SHUAI Jin-zhi  BAI Xu-hua
Abstract:
SEN virus is a non-enveloped virus with single-strand and circular DNA isolated from the serum of a patient with human immunodeficiency virus(HIV),which belongs to circoviridae.Its whole genome has 3900 nucleotides,which has 8 subtypes from SENV A-H,A and three OFR at least.Studies show that it has a strong association with transfusion-associated non-A to non-E hepatitis.This virus can infect alone or co-infected with type B hepatitis,C hepatitis and liver cancer. At present,there is still lack of enough evidence for SEN as a causative agent of hepertitis with unkown reason.
Keywords:SEN virus  Hepatitis  Route of transmission  Pathogenicity
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