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Detection of oncogene-related proteins with site-directed monoclonal antibody probes |
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| Authors: | Henry L. Niman |
| Abstract: | Sequences of oncogenes define related families and provide a large data bank for the production of synthetic peptides. These peptides can be used to produce site-directed monoclonal antibody probes, which identify oncogene-encoded and oncogene-related proteins. The creation and utilization of these probes for clinical laboratory analysis are discussed. |
| Keywords: | Screening diagnosis synthetic peptides hybridoma growth factor |